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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL12
All Species:
29.39
Human Site:
S214
Identified Species:
53.89
UniProt:
Q53G59
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53G59
NP_067646.1
568
63277
S214
A
K
K
E
R
E
E
S
L
P
N
L
L
Q
Y
Chimpanzee
Pan troglodytes
XP_001149345
684
76181
Q324
S
I
Q
E
R
R
P
Q
L
P
Q
V
L
Q
H
Rhesus Macaque
Macaca mulatta
XP_001094324
702
77633
S348
A
K
K
E
R
E
E
S
L
P
N
L
L
Q
Y
Dog
Lupus familis
XP_537119
568
63260
S214
A
K
K
E
R
E
E
S
L
P
D
L
L
Q
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8BZM0
568
63228
S214
A
K
K
E
R
E
E
S
L
P
D
L
L
Q
Y
Rat
Rattus norvegicus
Q8R2H4
568
63244
S214
A
K
K
E
R
E
E
S
L
P
D
L
L
Q
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518122
290
31726
Chicken
Gallus gallus
XP_419251
558
62467
S204
S
K
K
D
R
E
A
S
L
P
E
L
L
Q
Y
Frog
Xenopus laevis
Q6NRH0
564
63190
S210
N
R
H
E
R
E
K
S
L
P
Q
L
L
Q
Y
Zebra Danio
Brachydanio rerio
Q5U374
564
62914
Y210
N
R
K
E
R
E
P
Y
L
P
D
L
L
E
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
H253
N
V
A
E
R
R
Q
H
L
A
Q
V
L
Q
H
Honey Bee
Apis mellifera
XP_397065
620
68991
H260
N
V
T
E
R
R
Q
H
L
A
Q
V
L
Q
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001180470
684
75689
E325
S
E
I
T
K
E
D
E
F
L
D
L
T
P
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.8
80.9
99.8
N.A.
99.3
99.4
N.A.
50.3
87.1
91.5
89.7
N.A.
39.9
40.4
N.A.
40.6
Protein Similarity:
100
53.6
80.9
100
N.A.
99.8
99.8
N.A.
51
91
96.6
95.2
N.A.
57.9
57.7
N.A.
55.9
P-Site Identity:
100
40
100
93.3
N.A.
93.3
93.3
N.A.
0
73.3
66.6
60
N.A.
33.3
33.3
N.A.
13.3
P-Site Similarity:
100
66.6
100
100
N.A.
100
100
N.A.
0
86.6
80
80
N.A.
53.3
53.3
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
39
0
8
0
0
0
8
0
0
16
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
8
0
0
0
39
0
0
0
8
% D
% Glu:
0
8
0
77
0
70
39
8
0
0
8
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
16
0
0
0
0
0
0
24
% H
% Ile:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
47
54
0
8
0
8
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
85
8
0
70
85
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
31
0
0
0
0
0
0
0
0
0
16
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
16
0
0
70
0
0
0
8
0
% P
% Gln:
0
0
8
0
0
0
16
8
0
0
31
0
0
77
0
% Q
% Arg:
0
16
0
0
85
24
0
0
0
0
0
0
0
0
0
% R
% Ser:
24
0
0
0
0
0
0
54
0
0
0
0
0
0
0
% S
% Thr:
0
0
8
8
0
0
0
0
0
0
0
0
8
0
0
% T
% Val:
0
16
0
0
0
0
0
0
0
0
0
24
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
62
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _